• About Us
  • Advertise
  • Contact Us
  • DMCA
  • Follow on Google News
Wednesday, February 1, 2023
  • Login
National Age
  • Home
  • India
    • National
    • State News
  • World
  • Education
  • Lifestyle
    • Health & Fitness
    • Fashion
    • Travel
    • Food
  • Business
  • Tech
    • App News
    • Gadgets
  • Entertainment
  • Auto
  • Sports
  • Others
    • Agriculture
    • Science
    • Astrology
    • Finance/Money
No Result
View All Result
  • Home
  • India
    • National
    • State News
  • World
  • Education
  • Lifestyle
    • Health & Fitness
    • Fashion
    • Travel
    • Food
  • Business
  • Tech
    • App News
    • Gadgets
  • Entertainment
  • Auto
  • Sports
  • Others
    • Agriculture
    • Science
    • Astrology
    • Finance/Money
No Result
View All Result
National Age
No Result
View All Result
Home Lifestyle Health & Fitness

Study warns Diphtheria could become a major global threat

National Age by National Age
March 9, 2021
in Health & Fitness
0
Share on FacebookShare on Twitter

New Delhi: In a new health scare, a team of researchers from India, the UK and Russia, has found that Diphtheria, which is a relatively easily-preventable infection, has started to become resistant to several classes of antibiotics, and in future, it may even become immune to vaccination.

In a report, the team has also suggested that there was a possibility of the disease once more becoming a major threat across the globe because of the impact of COVID-19 on vaccination schedules in different parts of the world, coupled with a rise in the number of infections.

Diphtheria is a highly contagious infection. It can affect the nose and throat, and sometimes the skin. If left untreated it can prove fatal. In high-income countries, all babies are vaccinated against the infection. However, in low- and middle-income countries, the disease can still cause sporadic infections or outbreaks in unvaccinated and partially-vaccinated communities.

Read ThisAlso

Doctors at Sakra World Hospital do miraculous Neuro-rehabilitation of 36-year-old with severe head injury following bike accident in US

Doctors at Sakra World Hospital do miraculous Neuro-rehabilitation of 36-year-old with severe head injury following bike accident in US

January 18, 2023
‘Sassiest’ – Women-Led Sexual Wellness Startup to the Win – Bags the Award for Disruption

‘Sassiest’ – Women-Led Sexual Wellness Startup to the Win – Bags the Award for Disruption

January 18, 2023

The number of diphtheria cases reported globally has been increasing gradually. In 2018, there were 16,651 reported cases, more than double the yearly average for 1996-2017 (8,105 cases).

Diphtheria is primarily caused by the bacterium Corynebacterium diphtheriae and is mainly spread by coughs and sneezes, or through close contact with someone infected. In most cases, the bacteria cause acute infections, driven by the diphtheria toxin – the key target of the vaccine. However, non-toxigenic C. diphtheria can also cause disease, often in the form of systemic infections.

The researchers used genomics to map the infections, including a subset from India, where over half of the globally reported cases occurred in 2018. By analysing the genomes of 61 bacteria isolated from patients and combining these with 441 publicly available genomes that had been collected from across the world over 122 years (1896-2018), they build a phylogenetic tree – a genetic ‘family tree’ – to see how the infections are related, understand how they spread and assess the presence of antimicrobial resistance (AMR) genes and determine toxin variation.

The main disease-causing component of C. diphtheriae is the diphtheria toxin, which is encoded by the `tox’ gene. It is this component that is targeted by vaccines. In total, the researchers found 18 different variants of the `tox’ gene, of which several had the potential to change the structure of the toxin.

Diphtheria infections can usually be treated with several classes of antibiotics. While C. diphtheriae’s resistance to antibiotics have been reported, the extent of such resistance remains largely unknown.

The team looked for genes that might confer some degree of resistance to antimicrobials and they found that the average number of antimicrobial resistance genes per genome was increasing each decade. Genomes of bacteria isolated from infections from the most recent decade (2010-19) showed the highest average number of AMR genes per genome, almost four times as many on average than in the next highest decade, which was the 1990s.

In a report on their study published in Nature Communication today, the team said, “While our data does not, at present, highlight any efficacy concern in the currently used tox variant type 16 based diphtheria toxoid vaccine, the continually increasing toxin diversity and prevalence of non-toxigenic strains do however forecast a real possibility of vaccine escape and antitoxin treatment failure in future. While the current vaccine against diphtheria continues to remain largely effective, it is vital to conduct further in vitro and in vivo studies”.

The researchers were drawn from the Department of Biotechnology’s Translational Health Science and Technology Institute, Faridabad, Maharishi Valmiki Infectious Diseases Hospital, Delhi, Christian Medical College, Vellore, Tamil Nadu, World Health Organization, New Delhi, Ministry of Health and Family Welfare, New Delhi, Cambridge Institute of Therapeutic Immunology & Infectious Disease, University of Cambridge, Liverpool School of Tropical Medicine, UK, Gabrichevsky Research Institute for Epidemiology and Microbiology, Moscow, Russia, Northumbria University, Newcastle upon Tyne, UK. (India Science Wire)

National Age

See author's posts

Tags: acuteAMRantibioticsbabiesbacteriumcontagiouscoughCOVID-19diseasefatalgenomegenomicshealth scareIndiainfectionmap phylogenetic treenoseoutbreaksresistanceskinsneezethreatthroattoxinUKvaccinationworld
Share6Tweet4Share1SendShareSend
Previous Post

IIT-Madras Launches new programme to boost women leadership

Next Post

Raw drug repository for medicinal herbs established in CSIR-NBRI

National Age

National Age

Related Posts

Doctors at Sakra World Hospital do miraculous Neuro-rehabilitation of 36-year-old with severe head injury following bike accident in US
Health & Fitness

Doctors at Sakra World Hospital do miraculous Neuro-rehabilitation of 36-year-old with severe head injury following bike accident in US

January 18, 2023
‘Sassiest’ – Women-Led Sexual Wellness Startup to the Win – Bags the Award for Disruption
Health & Fitness

‘Sassiest’ – Women-Led Sexual Wellness Startup to the Win – Bags the Award for Disruption

January 18, 2023
The New Year's morning was started by Surtis with fitness
Health & Fitness

The New Year’s morning was started by Surtis with fitness

January 2, 2023
SHIAL will be the next top biggest online training platform in the world
Health & Fitness

SHIAL will be the next top biggest online training platform in the world

December 31, 2022
Fatt Lite – An amazing product for fat burn for busy men & women
Health & Fitness

Fatt Lite – An amazing product for fat burn for busy men & women

December 27, 2022
Sakal Group’s expert endeavor ‘Swasthyam’ spells out ways to be happy & healthy in life
Health & Fitness

Sakal Group’s expert endeavor ‘Swasthyam’ spells out ways to be happy & healthy in life

December 17, 2022
Next Post
Raw drug repository for medicinal herbs established in CSIR-NBRI

Raw drug repository for medicinal herbs established in CSIR-NBRI

Study kindles new hope for a cure for Parkinson’s Disease

Study kindles new hope for a cure for Parkinson’s Disease

Portal to provide all-inclusive information on SERB sanctioned projects

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

  • Trending
  • Comments
  • Latest
Pro Cricket Championship Trophy (PCCT) announced the schedule of their selection trials and matches today

Pro Cricket Championship Trophy (PCCT) announced the schedule of their selection trials and matches today

May 26, 2022
Now our E-store India has become an international company

Now our E-store India has become an international company

November 1, 2022
Rotary announces: 20th Global Poster Painting Competition

Rotary announces: 20th Global Poster Painting Competition

June 8, 2022
Influencerquipo presents Most Confident plus Size Influencer of the year- Jaanvi

Influencerquipo presents Most Confident plus Size Influencer of the year- Jaanvi

August 11, 2021
Pro Cricket Championship Trophy (PCCT) announced the schedule of their selection trials and matches today

Pro Cricket Championship Trophy (PCCT) announced the schedule of their selection trials and matches today

14
MPF Investments are mainly aimed at companies in the Indian Market

MPF Investments are mainly aimed at companies in the Indian Market

4

TECNO launches SPARK Power 2 Air: The new Power Play Entertainment device

2

PrivateCourt is all set to revolutionize the concept of Online Dispute Resolution

1
SERON-a name that the world trusts for home furnishings and Agro products

SERON-a name that the world trusts for home furnishings and Agro products

February 1, 2023
Jivraj9 reimagining the tea tradition through superior quality and innovation

Jivraj9 reimagining the tea tradition through superior quality and innovation

January 31, 2023
Rahil Khan Empowers Women with Self-Cupping Kit Launch at National Championship Praised by Nikat Zareen

Rahil Khan Empowers Women with Self-Cupping Kit Launch at National Championship, Praised by Nikat Zareen

January 31, 2023
How to attend the Global Startup Summit, 2023 on 4th February in Mumbai?

How to attend the Global Startup Summit, 2023 on 4th February in Mumbai?

January 31, 2023

Recent News

SERON-a name that the world trusts for home furnishings and Agro products

SERON-a name that the world trusts for home furnishings and Agro products

February 1, 2023
Jivraj9 reimagining the tea tradition through superior quality and innovation

Jivraj9 reimagining the tea tradition through superior quality and innovation

January 31, 2023
Rahil Khan Empowers Women with Self-Cupping Kit Launch at National Championship Praised by Nikat Zareen

Rahil Khan Empowers Women with Self-Cupping Kit Launch at National Championship, Praised by Nikat Zareen

January 31, 2023
How to attend the Global Startup Summit, 2023 on 4th February in Mumbai?

How to attend the Global Startup Summit, 2023 on 4th February in Mumbai?

January 31, 2023

www.nationalage.com, digital news and story platform bring you the news, articles, stories, and opinions on the latest happenings worldwide covering various sectors like nation, politics, and governance, social sector, review, foreign affairs, defence and security, latest review, lifestyle, entertainment, sports, technology, auto sectors, education, business and start-ups updates, Agriculture, Science, finance, money, food, and culture, etc.

If you have any query regarding Site, Advertisement, and any other issue, please feel free to contact at [email protected]

Follow Us

Browse by Category

  • Agriculture
  • App News
  • Astrology
  • Auto
  • Business
  • Education
  • Entertainment
  • Fashion
  • Finance/Money
  • Food
  • Gadgets
  • Health & Fitness
  • Lifestyle
  • National
  • Photography
  • Politics
  • Press Release
  • Religion
  • Science
  • Social Work
  • Sports
  • State News
  • Tech
  • Travel
  • World
SERON-a name that the world trusts for home furnishings and Agro products

SERON-a name that the world trusts for home furnishings and Agro products

February 1, 2023
Jivraj9 reimagining the tea tradition through superior quality and innovation

Jivraj9 reimagining the tea tradition through superior quality and innovation

January 31, 2023
Rahil Khan Empowers Women with Self-Cupping Kit Launch at National Championship Praised by Nikat Zareen

Rahil Khan Empowers Women with Self-Cupping Kit Launch at National Championship, Praised by Nikat Zareen

January 31, 2023
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Follow on Google News

Copyright © 2021 National Age

No Result
View All Result
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Home
  • Privacy Policy

Copyright © 2021 National Age

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In